Effect of Sutimlimab Treatment on Healthcare Resource Utilization in Patients with Cold Agglutinin Disease
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چکیده
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15 صفحه اولImpact of Dronedarone Treatment on Healthcare Resource Utilization in Patients with Atrial Fibrillation/Flutter
BACKGROUND The ATHENA (A Placebo-Controlled, Double-Blind, Parallel Arm Trial to Assess the Efficacy of Dronedarone 400 mg bid for the Prevention of Cardiovascular Hospitalization or Death from Any Cause in Patients with Atrial Fibrillation/Atrial Flutter) trial demonstrated a significant reduction (26%) in the rate of first cardiovascular (CV) hospitalization in dronedarone-treated patients wi...
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T HE COLD AGGLUTININ SYNDROME (C.A.S.) is characterized by high-titre cold agglutinins, a hemolytic anemia, Raynaud phenomena in the cold, various degrees of hemoglobinuria, and sometimes gangrene. Because of the hemolysis, the syndrome is most often classified as an autoimmune hemolytic anemia. However, treatment with ACTH, corticosteroids or splenectomy, most often used in this condition, has...
متن کاملCold agglutinin disease.
Cold agglutinin disease is a rare and poorly understood disorder affecting 15% of patients with autoimmune hemolytic anemia. We reviewed the clinical and pathologic features, prognosis, and management in the literature and describe our institutional experience to improve strategies for accurate diagnosis and treatment. Retrospective analysis identified 89 patients from our institution with cold...
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Dr Gyger and colleagues, in reply to our work on granulocyte colony-stimulating factor (G-CSF) bone marrow (BM) purging, have pointed out three aspects of the problem: the possible negative balance of marrow cells after short-term G-CSF administration, the need for at least two cytokines for priming BM stem cells (BMSC), and the probable contamination of BM harvest. Overall, we agree on each of...
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ژورنال
عنوان ژورنال: Blood
سال: 2020
ISSN: 0006-4971,1528-0020
DOI: 10.1182/blood-2020-139738